Απ Bioengineering student

The RNA folding problem: an Integer Linear Programming approach

Ribonucleic acid, as well-known as RNA, is a polymeric molecule essential in various biological phenomena. Unlike DNA, this macromolecule is found in nature as a single-strand folded onto itself, rather than a paired double-strand and some of its principal functions are coding, decoding, regulation, and expression of genes.

RNA folding is the process by which a linear ribonucleic acid molecule acquires secondary structure through intramolecular interactions, so the RNA folding problem consists of predicting the secondary structure of a molecule given only its nucleotide sequence.

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See more: Chapter 6, Integer Linear Programming in Computational and Systems Biology: An entry-level text and course, Dan Gusfield